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Author

V. Pavshintsev

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Review Open access Feb 2026

Resveratrol for Atherosclerosis: Potential Mechanisms

as it enhances brain energy metabolism and diminishes oxidative stress. Likewise, another investigation revealed that RV possesses anti-inflammatory and antioxidant characteristics. These properties can help suppress or prevent age-related cardiovascular diseases. Notably, RV has been shown to enhance cardiac contracti...

A. V. Poznyak, S.M. Kozlov, Gulalek A. Babayeva et al. · 0 citations
Open access Sep 2026

Semaglutide Attenuates Inflammatory Macrophage Polarization and Promotes Changes Associated with Mitochondrial Biogenesis Through cAMP-Dependent Signaling

Background/Objectives: Chronic metabolic inflammation is associated with pro-inflammatory macrophage activation and mitochondrial dysfunction. Semaglutide, a widely used GLP-1 receptor agonist, has been reported to possess systemic anti-inflammatory properties, but its action on human macrophages, especially in the con...

V. Pavshintsev, Aleksandra Zh Erbaeva, Alexey Vatlin et al. · 0 citations
Review Open access Sep 2026

Mitochondria in Parkinson disease: Genetic and epigenetic components

Advances in understanding mitochondrial biology have enabled the development of novel therapeutic approaches, including activators of the PINK1/Parkin pathway, inhibitors of LRRK2 and α-synuclein aggregation, and strategies promoting mitochondrial biogenesis and intercellular transfer, offering potential for disease mo...

A. V. Poznyak, V. Pavshintsev, Aleksandra O. Utkina et al. · 0 citations

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