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Author

V. Poroikov

2 papers indexed here

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Review Sep 2026

Computational approaches to predicting xenobiotic metabolism by the human gut microbiota.

INTRODUCTION The human gut microbiota significantly influences drug pharmacokinetics and pharmacodynamics, driving interindividual variability in efficacy and toxicity. As experimental characterization of microbiome-mediated metabolism remains resource-intensive, computational prediction has emerged as an auxiliary str...

A. Kolodnitsky, A. Lagunin, V. Poroikov · 0 citations
Open access Aug 2026

Computational Prediction of the Severity of Adverse Drug Reactions Caused by Drug–Drug Interactions

Background/Objectives: Adverse drug reactions (ADRs) caused by drug–drug interactions (DDIs) represent an important problem in pharmacotherapy, especially in patients receiving multiple medications. Most computational approaches to DDI-associated ADR prediction formulate the task as a binary classification, but they do...

V. S. Sukhachev, S. M. Ivanov, D. Filimonov et al. · 0 citations

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