Impact of Organic Solvents, Surfactants, and Nonfunctionalized PEGs on PEGylation Reaction Yield
The optimization of PEGylation reaction yield is critical for the efficient production of therapeutic bioconjugates. This study systematically investigates the influence of three distinct classes of additives -organic cosolvents, nonreactive poly(ethylene glycols) (PEGs) of varying molecular weights, and surfactants- o...