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V. Steeples

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Open access Jul 2026

Unmasking Supervillin: SVIL haploinsufficiency causes hypertrophic cardiomyopathy by impairing mechanotransduction and cellular energetics

SVIL-associated cardiomyopathy is established as a mechanistically distinct form of HCM and drugs targeting mitochondrial bioenergetics may be a therapeutic strategy in patients with SVIL-associated cardiomyopathy.

Yifan J. Li, Y. Psaras, V. Steeples et al. · 0 citations

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