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Open access Aug 2026

101 Independent replication and validation of nanopore-based long read sequencing and methylome classification for rapid brain tumour diagnosis

Integrated histopathological-molecular analysis is essential to diagnose and guide precision therapies in brain tumours. Whilst standard of care (SoC) diagnostics takes weeks, long read sequencing (LRS) on Oxford Nanopore Technology (ONT) platform and bioinformatics research tools provide rapid diagnosis within h...

Vassili Crispi, L. Ames, J. Stockton et al. · 0 citations
Open access Aug 2026

76 Metabolic Heterogeneity in Brain Tumours: Distinguishing Brain Metastases from Glioblastomas

Brain metastases account for nearly 20% of cancer-related deaths and have a five-year survival rate of 2.4%, most commonly arising from breast and lung cancers. Despite therapeutic advances, prognosis remains poor, highlighting the need for novel treatment strategies. Metabolic reprogramming is a hallmark of canc...

Ishana Rajgopal, Bryan P. Marzullo, Sana Manan et al. · 0 citations

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