Author

V. Wykes

3 papers indexed here

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Review Open access Oct 2026

104 The utility of multiparametric MRI in reducing diagnostic uncertainty for CNS lymphoma

Diagnostic uncertainty represents a significant barrier to the timely initiation of treatment for central nervous system lymphoma (CNSL). Our previous 10-year retrospective service evaluation project demonstrated that concordance on multiparametric MRI (MPMRI) could be used as a radiological predictor of CNSL in...

George Phenix, Aimee Goel, Ute Pohl et al. · Neuro-Oncology · 0 citations

Open access Oct 2026

171 Characterisation of macrophage and microglial phenotype within resected glioblastoma tissue and potential for re-polarisation using precision cut human tissue slices

Glioblastoma is the most common and most aggressive primary brain tumour in adults, representing one of the most formidable challenges in oncology. Despite surgical resection, radiotherapy and chemotherapy, median survival rates are low (12-18 months) with fewer than 10% of patients surviving beyond five years. These...

Emma Welsh, Zhi Li, Jamie Cowley et al. · Neuro-Oncology · 0 citations

Open access Aug 2026

101 Independent replication and validation of nanopore-based long read sequencing and methylome classification for rapid brain tumour diagnosis

Integrated histopathological-molecular analysis is essential to diagnose and guide precision therapies in brain tumours. Whilst standard of care (SoC) diagnostics takes weeks, long read sequencing (LRS) on Oxford Nanopore Technology (ONT) platform and bioinformatics research tools provide rapid diagnosis within h...

Vassili Crispi, L. Ames, J. Stockton et al. · Neuro-Oncology · 0 citations