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Author

V. Yurchenko

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Open access Oct 2026

Leishmania (Mundinia) species differ in glycoconjugate composition and induce variable levels of NO via TLR2 and TLR4.

Leishmania (Mundinia) species have attracted increasing attention due to their ancestral phylogenetic position, broad distribution, and ability to exploit non-sand fly vectors. However, the structure and immunomodulatory role of their surface glycoconjugates remain poorly understood. We comparatively characterized the...

R. P. Soares, V. Yurchenko, Petr Volf et al. · 0 citations
Open access Aug 2026

A p32 family RNA editing factor acts in mitochondrial ribosome biogenesis

These findings redefine trypanosomal p22 as a dual-function coordinator of mitochondrial gene expression and reveal that the ancestral role of the p32 family is associated with mitochondrial translation.

Prashant Chauhan, Ingrid Sveráková-Škodová, J. T. Wong et al. · 0 citations
Open access Aug 2026

Leishmania guyanensis controls endogenous viral replication by a canonical RNA interference pathway

This study investigated effectors in the canonical RNAi response and the Piwi protein of the human pathogen L. (Viannia) guyanensis by gene ablation and identified Dicer-like and Argonaute 1 proteins of the canonical RNAi pathway as critical for controlling viral RNA levels, suggesting that control of viral replication...

Donnamae Klocek, Rhys H. Parry, G. A. Kay et al. · 0 citations

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