Plasma Gelation as an Overlooked Determinant of Transfection Efficiency in Protein Corona‐Coated Lipid Nanoparticles: Implications for In Vitro–In Vivo Translation
A combination of complementary approaches, including dynamic light scattering, fluorescence‐activated cell sorting, confocal fluorescence microscopy, raster image correlation spectroscopy, and functional assays evaluating TE and cell viability, demonstrates that this gel‐like matrix restricts LNP diffusion in the extra...