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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Van-The Le

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Oct 2026

DeepRAGIL-2: a retrieval-augmented protein language model framework for sensitive and accurate prediction of IL-2-inducing peptides.

DeepRAGIL-2 is presented, a sequence-based framework integrating ESM-2 protein language model embeddings, dual-window convolutional feature extraction, and retrieval-augmented embedding fusion (RAG) into a unified classification pipeline, establishing a framework applicable in principle to cytokine-specific immunologic...

Juan Peter Timothy Yuune, Van-The Le, Yu-Yen Ou · 0 citations
Sep 2026

NeoGen-BC: A synergistic framework combining generative protein language models and multi-window deep learning for designing shared neoantigens in breast cancer.

Breast cancer, particularly hormone receptor-positive (HR+) and triple-negative (TNBC) subtypes, is often immunologically "cold," limiting immunotherapy efficacy. Neoantigen-based vaccines hold promise but face challenges from inaccurate identification and overreliance on HLA binding affinity, which poorly captures tru...

Van-The Le, Juan Peter Timothy Yuune, Jiun-I Lai et al. · 0 citations

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