Vasanthakrishnan Radhakrishnan Balasubramaniam

Structural characterization of hibernating ribosomes in four Gram-negative pathogenic bacteria

Ribosome hibernation is a conserved bacterial stress-response mechanism that promotes translational shutdown and enhances survival under adverse conditions, contributing to persistence and tolerance to ribosome-targeting antibiotics. Here, we report high-resolution cryo-electron microscopy (cryo-EM) structures (2.5...