Isoindole-Based Multicomponent Synthesis of Pyrimido[6,1,2- cd ]pyrrolizine Fluorophores with Unsymmetrical Urea Handles: Photophysical, Theoretical, and Antifungal Imaging Studies
A diversity-oriented, one-pot synthetic strategy was successfully employed to generate a library of pyrimido[6,1,2-cd]pyrrolizine (PP)-based fluorophores incorporating unsymmetrical urea functionality, which function as versatile fluorescent probes and pharmacophores. These PP derivatives, efficiently constructed via...