Venkata Naga Sai Nikhil Bhagavatula

Synthesis of 2, 3-disubstituted imidazo [1, 2-a] pyrimidines as versatile intermediates toward oroidin and modified CK-666 analogues

Nitrogen-rich heterocycles constitute privileged structural motifs in natural products and pharmaceuticals, forming the core architecture of numerous bioactive alkaloids, antibiotics, and approved drugs through their selective interactions with diverse biological targets. Among these, the imidazo[1,2-a] pyrimidine scaf...