CDHR5 and UPB1 expression associated with promoter methylation in sarcomatoid differentiated clear cell renal cell carcinoma
Clear cell renal cell carcinoma (ccRCC) represents the most frequent histological subtype of renal cell carcinoma (RCC). Sarcomatoid (de)differentiation is associated with metastatic dissemination and dismal prognosis. Altered DNA methylation occurs during ccRCC progression but a specific role in the emergence of sarco...