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This chapter presents a step-by-step guide to ChAseR, an R package to analyze chromatin architecture using network-based approaches, and illustrates the workflow on a promoter-centered chromatin network derived from human monocytes.
This paper distinguishes technical reliability from trust in AI-supported clinical decision-making, arguing that the two belong to distinct registers that current debates tend to elide and proposes replacing the expression "trustworthy AI" with "technically reliable AI," a distinction that relocates the conditions of t...
PTBP1 is established as a critical regulator of AML cell fitness and a clinically actionable therapeutic combination that exploits AML dependency on PTBP1-CDC42 signaling to enhance the efficacy of venetoclax-based regimens is identified.
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