Author

Vibhuti Patel

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Open access Oct 2026

Development of a messenger RNA therapy for schizophrenia.

BACKGROUND Few gene-disease associations identified by human genetic studies lead to new drugs that advance to first-in-human trials. Schizophrenia exemplifies this translational gap: thousands of gene-disease associations have been reported, but antipsychotics act via mechanisms introduced in the 1950s. To close the g...

N. Simons, Vibhuti Patel, Hao-Yuan Li et al. · Biological Psychiatry · 0 citations