Sep 2026
The post-transcriptional regulator HuR promotes immune evasion in pancreatic ductal adenocarcinoma.
The tumor microenvironment (TME) of pancreatic ductal adenocarcinoma (PDAC) is characterized by restrained function of effector T cells that drives resistance to immunotherapy. While tumor-extrinsic stroma and myeloid cells have been shown to mediate PDAC immune evasion, the role of tumor-intrinsic post-transcriptional...
Yi-Fei Guo, Jennifer M. Finan, Alexandra Q. Bartlett et al.
· Cancer immunology research · 0 citations