Author

Von G. Samedi

2 papers indexed here

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Open access Aug 2026

EphA4 Mediates Pro- and Antitumoral Effects Through Upstream Negative Regulation of AKT in Head and Neck Squamous Cell Carcinoma.

Head and Neck Head and Neck Squamous Cell Carcinoma (HNSCC) is driven by an immunosuppressive tumor microenvironment (TME). We examined the immune-modulatory role of EphA4 in HNSCC using spatial analysis, multi-compartment RNA-sequencing from Oral Cavity Squamous Cell Carcinoma (OCSCC), and three genetically engineered...

S. Corbo, Khalid N. M. Abdelazeem, D. Nguyen et al. · Cancer immunology research · 0 citations

Open access Sep 2026

Dissociated response to immune checkpoint inhibition in head and neck squamous cell carcinoma is common and exhibits distinct clinical outcomes.

Immune checkpoint inhibition (ICI) constitutes the first-line therapy for relapsed/metastatic head and neck squamous cell carcinoma (HNSCC) despite low response rates. Some patients treated with ICI experience dissociated response (DR), the co-existence of responding and progression lesions. DR prevalence and prognosti...

Alice N. Weaver, S. Keysar, Aarti Dureja et al. · Cancer Research Communicatio... · 0 citations