Author

Vrinda Kalia

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Open access Sep 2026

Astrocyte-derived extracellular vesicle phosphorylated TDP-43 as a blood-based biomarker for amyotrophic lateral sclerosis.

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by central nervous system (CNS) neuroglial TAR DNA-binding protein 43 (TDP-43) pathology in ~90-95% of cases. Non-invasive biomarkers are critically needed to reduce diagnostic delay, enable patient stratification, and assess treatme...

Tanya H. Butt, Madeleine D. Strait, Lina Marcinczyk et al. · Neurobiology of Disease · 0 citations

Sep 2026

Circulating metabolomic and chemical exposomics signatures as potential biomarkers for long-term radon exposure.

Radon is a radioactive gas and a lung carcinogen, yet lacks established blood biomarkers for long-term exposure. We aimed to identify circulating metabolomic and exposomics signatures correlated with reconstructed radon-222 exposure. Metabolites and chemical exposomes were profiled using liquid and gas chromatography-h...

Vrinda Kalia, A. Rajendrakumar, Rodrigo Cruz-Nieto et al. · Environmental Research · 0 citations