Author

Vrushabh Patil

3 papers indexed here

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Review Sep 2026

Recent Advances and Challenges in Addressing Drug-induced Liver Injury (DILI): Mechanisms and Nanocarrier Solutions.

INTRODUCTION Drug-Induced Liver Injury (DILI) is a leading cause of drug attrition, postmarketing withdrawals, and acute liver failure. It presents a major barrier to the safe development of new therapeutics, particularly due to its unpredictable pathogenesis and the lack of reliable preclinical models. Current diagnos...

Ashok Thulluru, Vrushabh Patil, C. Jangme et al. · Mini-Reviews in Medical Chem... · 0 citations

Sep 2026

Nanostructured Cubosomal Gels for Targeted Drug Delivery in Rheumatoid Arthritis: Advances in Nanomedicine and Therapeutic Nanotechnology.

Introduction/ Objective: Rheumatoid Arthritis (RA) is an autoimmune disease characterized by chronic inflammation of the synovial joints, leading to joint destruction and systemic complications. Existing therapies, such as Disease-Modifying Antirheumatic Drugs (DMARDs) and Nonsteroidal Anti-Inflammatory Drugs (NSAIDs),...

Ashok Thulluru, C. Jangme, Vrushabh Patil · Recent Advances in Drug Deli... · 0 citations

Review Sep 2026

Heat Shock Protein 90 as a Master Regulator of Multidrug Resistance: Small-molecule Inhibitors, Prodrugs, Hybrid Molecules, Antibody-drug Conjugates, and Nanotechnology-based Delivery Systems.

INTRODUCTION/OBJECTIVE Multidrug Resistance (MDR) remains a major obstacle to effective cancer chemotherapy, driven by multiple interconnected mechanisms, including overexpression of ATP-binding Cassette (ABC) transporters, enhanced DNA repair, apoptosis evasion, and protumorigenic microenvironmental factors. Heat Shoc...

Sundeep Kadasi, A. Kholkumbe, C. Jangme et al. · Mini-Reviews in Medical Chem... · 0 citations