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Open access Sep 2026

A streamlined hybrid-capture and genome-wide multi-omic platform for highly sensitive ctDNA minimal residual disease monitoring

Background Circulating tumor DNA (ctDNA) analysis has revolutionized minimal residual disease (MRD) monitoring, but conventional tumor-informed amplicon-based sequencing (AMP) is limited by the narrow variant capacity and diversity. Hybrid capture-based sequencing (HYB) is more versatile and enables both tumor-informed...

T. Nguyen, Van-Anh Nguyen Hoang, C. Huynh et al. · 0 citations
Open access Aug 2026

CALFP-MHC: Interpretable Pan-Allelic Prediction of Peptide-MHC Binding and Presentation Using Chemically Grounded Fingerprints and Contrastive Learning

CALFP-MHC demonstrates that grounding residue representations in molecular chemistry, rather than sequence symbols alone, improves both robustness and interpretability in peptide–MHC binding prediction.

My-Diem Nguyen Pham, T. Ho, H. Nguyen et al. · 0 citations

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