W. Abdelmoula

PaSTel: Anchoring Histology in Spatial Transcriptomics via Multi-Scale Hierarchical Bio-Prior Contrastive Pretraining

PaSTel is introduced, a hierarchical multimodal pretraining framework that integrates biological priors at three levels that consistently outperforms existing vision and vision-omics encoders, demonstrating that incorporating multiscale biological priors yields more informative and transferable representations for spat...