W. Aboulthana

Development of new imidazopyridine-based chalcones hybrids as potent antidiabetic and antioxidant agents: synthesis, in silico and in vitro evaluation

A novel series of six imidazopyridine-based chalcone hybrids is synthesized and evaluated their in vitro biological activities, including total antioxidant capacity, iron-reducing power, and radical scavenging (DPPH, ABTS, NO), as well as antidiabetic potential against α-amylase, α-glucosidase, and aldose reductase.