Beyond PD-L1/PD-1: expression of PVR/TIGIT and TNFRSF14/BTLA axes in response to Helicobacter pylori and in gastric cancer lesions
Abstract Gastric cancer (GC) has a high mortality rate worldwide, mainly due to late detection and lack of effective treatments. Immune checkpoint (ICs) inhibitors have revolutionized cancer treatment; however, a substantial percentage of patients with GC do not respond to this treatment, which may be related to aspect...