Author

W. Backes

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Open access Aug 2026

Disentangling MRI-derived blood–brain barrier leakage into vascular permeability and surface area

In neurovascular and neurodegenerative diseases, blood–brain barrier (BBB) disruption can be subtle and diffuse, and MRI-derived measures are confounded by microvascular architecture. Therefore, we aimed to disentangle the MRI-derived blood–brain barrier leakage rate (Ki) into intrinsic vascular permeability (P) and su...

Damon Verstappen, J. D. de Jong, P. Voorter et al. · Journal of Cerebral Blood Fl... · 0 citations

Open access Sep 2026

Volumetric and functional connectivity alterations of the thalamus and thalamic nuclei groups in drug-resistant focal epilepsy: A 7T MRI study.

Ventral, medial, and posterior nuclei metrics show promise as imaging biomarkers of disease burden and seizure severity, thus encouraging further research into both structural and functional properties of thalamic nuclei in focal epilepsy.

D. Uher, L. Vermeer, J. Jansen et al. · Neuroradiology · 0 citations

Open access Jul 2026

Quantitative Relationship Between White Matter Hyperintensity Volume and Fazekas Score on Brain MRI

BACKGROUND: The Fazekas score is widely used to grade white matter hyperintensities (WMHs) in cerebral small vessel disease, yet the equivalent volume of each grade is unclear. We quantified the correspondence between Fazekas scores and WMH volume, normalized ratios, and derived conversion equations across populations....

Yuyuan Xu, Francesca M. Chappell, M. V. Valdés Hernández et al. · Stroke · 0 citations