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W. Baumgärtner

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Open access Sep 2026

Intestinal oxysterol remodeling underlies severe COVID-19 in an aged hamster model.

Age is a critical determinant of COVID-19 severity, yet the underlying metabolic mechanisms driving disease progression remain poorly understood. Using a well-characterized Syrian hamster model, we investigated how aging shapes intestinal and systemic sterol metabolism during SARS-CoV-2 infection. Young (7-10 weeks) an...

AhmedElmontaser Mergani, Katrin Wirz, Wencke Reineking et al. · 0 citations

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