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Author

W. Chatila

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Open access Sep 2026

Integrated clinicogenomic analysis reveals the evolution and metastatic tropisms of advanced colorectal cancer

SUMMARY We performed an integrated clinical and genomic analysis of over 7,000 consecutively sequenced colorectal cancer (CRC) samples to comprehensively characterize genetic drivers and metastatic tropisms of CRC. We find that genomic evolutionary changes, such as clonal mutations and oncogenic mutant allele imbalance...

Paolo Manca, H. Walch, Jierui Xu et al. · 1 citation
Aug 2026

Molecular Alterations in Patients of Color with Advanced Cutaneous and Unknown Primary Melanomas.

BACKGROUND Cutaneous melanoma is rare in Patients of Color (POC), and the genomics are not well understood. OBJECTIVE Describe MAPK drivers and tumor mutational burden (TMB) of cutaneous and unknown primary (CUP) melanoma in POC and compare them to non-Hispanic White (NHW) patients. METHODS We analyzed a retrospect...

J. Ross, Vanessa R. Weir, Leore Lavin et al. · 0 citations

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