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Review Oct 2026

Supraclavicular artery island flap for head and neck reconstruction: Our experience and exploratory analysis of risk factors.

OBJECTIVE The supraclavicular artery island flap (SCAIF) is being increasingly used for reconstruction of complex head and neck defects as an alternative to the traditional free flap or pedicled pectoralis flap. Here, we describe our experience with SCAIF for oncologic head and neck reconstruction and aim to identify p...

Joshua C. Hwang, Chloe Cottone, W. Magner et al. · 0 citations
Sep 2026

Auranofin Sensitizes Oral Squamous Cell Carcinoma to PD-1 Blockade Through DUSP1-Associated Macrophage Reprogramming.

Oral squamous cell carcinoma (OSCC) is frequently refractory to immune checkpoint blockade, in part because the tumor microenvironment is enriched with immunosuppressive, M2-like tumor-associated macrophages. Auranofin (ARN), an FDA-approved thioredoxin reductase inhibitor, induces oxidative and proteotoxic stress and...

Li-Xia Zhang, C. R. Nascimento, W. Magner et al. · 0 citations

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