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W. Steyaert

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Open access Aug 2026

Sequence architecture shapes human allele frequencies through ectopic gene conversion

It is shown that for a substantial fraction of human variation this assumption fails, and fails predictably: ectopic gene conversion reintroduces the same nucleotide change generation after generation, at rates strongly structured by two fixed properties of genome architecture, homologous template length and donor-acce...

W. Steyaert · 1 citation

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