Wafaa Abd Alaziz

Synthesis and Polymerization of Some New Derivatives of Cefalexin Drug and Evaluating Its Antimicrobial Activities

The primary amino group of cefalexin was condensed with selected aldehydes, which contain electron-donating and electron-withdrawing substituents, in ethanol under reflux conditions for 6–8 h in the presence of glacial acetic acid as a catalyst, to give a series of cefalexin Schiff bases (W1–W5; 55–82%). These Schiff b...