Wan-Chao Zhang

Ferroptosis-related genes influence AML risk through immune cell–mediated pathways: a Mendelian randomization study with mediation analysis

Acute myeloid leukemia (AML) is driven by complex interactions among genetic alterations, metabolic reprogramming, and immune microenvironment dysregulation. Ferroptosis, a form of iron-dependent regulated cell death linking iron metabolism with immune regulation, has been implicated in AML; however, its causal interpl...