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Wan-Ru Zhuang

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Open access Sep 2026

Macrophage Trogocytosis of Tumor Cells Drives the Immunosuppression of Tumor Microenvironment

ABSTRACT Despite considerable advances in cancer immunotherapy, the persistent immunosuppressive tumor microenvironment (TME) seriously limits its performance in solid tumors. Here, we reveal that trogocytosis—an intercellular membrane transfer process—between tumor‐associated macrophages (TAMs) and cancer cells serves...

Chao Liang, Jia-Qi He, Wan-Ru Zhuang et al. · 0 citations

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