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Author

Wan-Ying Zhang

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Oct 2026

Enolase 1 inhibition potentiates sorafenib efficacy in hepatocellular carcinoma through ferroptosis induction.

Enolase 1 (ENO1) is overexpressed in hepatocellular carcinoma (HCC) and correlates with poor patient prognosis, as evidenced by TCGA and Kaplan-Meier (KM) analysis. This study demonstrates that targeting ENO1 with its specific inhibitor, ENOblock, markedly enhances the antitumor efficacy of sorafenib in HCC cells. The...

Qiu-Shuang Ma, Xiao-Man Zhao, Wan-Ying Zhang et al. · 0 citations

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