Open access
Sep 2026
A Multiscale Quantitative Systems Pharmacology Platform for Early Screening of MMAE-Based Antibody-Drug Conjugates.
Antibody-drug conjugates (ADCs) have become an important therapeutic modality in the cancer field. However, their complex structural characteristics bring huge challenges to ADC development. Quantitative systems pharmacology (QSP) models can help integrate multi-scale data, providing mechanistic support. Nevertheless,...
Qiao-Ning Li, Ling Wang, Shan-Shan Bi et al.
· European Journal of Pharmace... · 0 citations