Author

Wangzhe Fan

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Open access 2026

Mesenchymal Stem Cell-Derived Exosomes Loaded with Isoliquiritigenin Promote Skin Wound Healing via Regulation of the TGF-β1 Signaling Axis

: Objective: Isoliquiritigenin (ISO) has potential wound-repair activity, but its poor aqueous solubility and incompletely defined mechanism may limit therapeutic application. In this study, we developed isoliquiritigenin-loaded mesenchymal stem cell-derived exosomes (Exo-ISO), aimed to evaluate their effects on wound...

Wang-Zhe Fan, Kang-Dao Liu, Bing-Bing Zhang et al. · Biocell (Mendoza) · 0 citations

Open access Jul 2026

Agreement and discordance between the modified thoracolumbar injury classification and severity score and the thoracolumbar AOSpine injury score in guiding surgical decision-making for thoracolumbar fractures: a comparative study.

For burst fractures with intervertebral disc involvement, mTLICS tends to recommend surgery more often, reflecting a difference in classification behaviour rather than a demonstrated clinical advantage, and mTLICS and TL AOSIS show substantial concordance as decision-support tools for thoracolumbar fractures.

Han Zhang, Junwei Feng, Hui-Bin Luo et al. · BMC Surgery · 0 citations