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Author

Wang Zheng

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2 papers indexed here

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Open access Sep 2026

CD81 drives immune evasion in radioresistant glioblastoma by blocking selective autophagic degradation of CD274/PD-L1.

Glioblastoma multiforme (GBM) is the most aggressive primary brain tumor, for which radiotherapy constitutes the key component of standard comprehensive treatment; however, tumor relapse could inevitably arise from intrinsically radioresistant GBM subclones. Radiotherapy exerts biphasic regulatory effects on the tumor...

L. Zeng, Yu-Chuan Zhou, L. Cai et al. · 0 citations
Sep 2026

SEPT5 confers radioresistance by suppressing GSDME-dependent pyroptosis and antitumor immunity in non-small cell lung cancer.

Non-small cell lung cancer (NSCLC) remains a major cause of cancer mortality worldwide, and radioresistance significantly compromises the efficacy of radiotherapy. However, the precise molecular determinants governing NSCLC radiosensitivity remain incompletely defined. Here, we identify SEPT5 as a key regulator of radi...

Jun-Miao Wen, Wang Zheng, Bo-Yan Wang et al. · 0 citations

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