Wang-Zhi Li

Ricolinostat restrains osteoclastogenesis through HDAC6-associated regulation of p65 stability.

Excessive osteoclast activity is a central driver of pathological bone loss in osteoporosis; however, the mechanisms governing osteoclast differentiation remain incompletely understood, and current therapeutic options remain limited in efficacy. Therefore, we performed high-throughput drug screening to identify candida...