Review
Open access
Aug 2026
Gene-Environment Interaction Between Heavy Alcohol Use and PNPLA3 rs738409 in Incident Cirrhosis: Evidence From a Diverse U.S. Cohort.
BACKGROUND Alcohol-associated cirrhosis develops in only a subset of people with heavy alcohol exposure, suggesting that inherited susceptibility modifies risk. We evaluated whether PNPLA3 rs738409 carrier status modifies the association between survey-derived alcohol intensity and incident cirrhosis. METHODS We perf...
Krushi B. Suresh, Ronak Bhatia, Muhammad Sajawal et al.
· Clinics And Research in Hepa... · 0 citations