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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

Wayland W. L. Cheng

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2 papers indexed here

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Open access Sep 2026

Molecular determinants of ligand recognition and efficacy in the TRPM3 voltage sensor-like domain

Transient receptor potential melastatin 3 (TRPM3) is a calcium-permeable ion channel implicated in chronic pain and developmental and epileptic encephalopathies. The voltage sensor-like domain (VSLD) is a major site of pharmacological modulation, but the molecular determinants of ligand recognition and efficacy remain...

Vikram Dalal, V. Rangari, Samuel Eriksson Lidbrink et al. · 0 citations
Open access Aug 2026

Characterization of an open-channel structure and lateral conduction pathway in the cation-selective pentameric ligand-gated ion channel, ELIC

Using molecular dynamics, computational electrophysiology, and single-channel recordings, Arcario et al. identify a cryptic extracellular lateral fenestration in the pentameric ligand-gated ion channel, ELIC, that becomes the dominant cation conduction pathway. Expansion of this pathway is required to reproduce experim...

Mark J. Arcario, Elizabeth J. Wu-Chen, Yuna Shim et al. · 0 citations

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