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Author

Wei Cao

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Sep 2026

Channel-Guided Engineering of Tryptophan Synthase β-Subunit for High-Level Biosynthesis of the Garlic Bioactive Compound S-Allyl- l -Cysteine

S-Allyl-l-cysteine (SAC) is a bioactive organosulfur compound from aged garlic that has attracted considerable interest for its health-promoting properties. Here, we developed a channel-guided engineering strategy to enhance SAC biosynthesis using the β-subunit of tryptophan synthase (TrpB). Genome mining guided by c...

Zhao-Lin Song, De-Quan Liu, Zhao Zhang et al. · 0 citations

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