Time-varying prognostic value of circulating tumor DNA in urothelial carcinoma: a systematic review and reconstructed patient-data meta-analysis.
Circulating tumor DNA (ctDNA) increasingly guides adjuvant therapy and surveillance in urothelial carcinoma (UC), yet whether its prognostic effect is adequately summarized by a single pooled hazard ratio (HR), which assumes proportional hazards (PH), has not been formally evaluated. We searched five sources for studie...