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Author

Wei-Chen Xu

2 papers indexed here

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Open access Sep 2026

Targeting Macrophage‐Mediated Lymphatic Immunosuppression to Prevent Tumor Recurrence After Microwave Ablation

ABSTRACT Microwave ablation (MWA) is an effective locoregional therapy for solid tumors, but recurrence caused by minimal residual disease remains a clinical challenge. Although immunotherapy offers a strategy to prevent recurrence, the role of tumor‐draining lymph nodes (TDLNs) in post‐ablation immune regulation remai...

Xuexia Shan, Yu-Ting Shen, Xiao-Dong Hou et al. · 0 citations
Open access Aug 2026

Defect‐Engineered BiO2‐X Nanosheets Mediate Sono‐Thermomechanical ECM Remodeling for Hepatocellular Carcinoma Immunotherapy

ABSTRACT Immune checkpoint blockade for hepatocellular carcinoma (HCC) is frequently limited by the extracellular matrix (ECM). Through transcriptomic profiling, we identify that acquired anti‐PD‐1 resistance in HCC models is closely associated with prominent Fibronectin 1 (Fn1) upregulation within the tumor microenvir...

Huimin Tian, Shen Zhang, Bo-Lin Wu et al. · 0 citations

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