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Open access 2026

Nonlinear and Seasonally Heterogeneous Responses of Land Surface Temperature to Land Use and Urban Functional Zone: A Case Study of Xi'an, China

Urban heat island (UHI) effects increasingly threaten sustainable urban development under the combined pressures of climate change and rapid urbanization. Nevertheless, most existing studies focus on single seasons or extreme summer events, with limited attention to the nonlinear and seasonally heterogeneous relationsh...

Yue-Jing Gao, Li Han, Wei Ding et al. · 0 citations
Open access Sep 2026

Repeat region engineering of Cas13a crRNA enables conformational gating-based autocatalytic CRISPR biosensing

The findings redefine the crRNA scaffold as a versatile signaling node and provide a generalizable framework for developing high-sensitivity, self-amplifying CRISPR biosensors through topology-driven guide RNA engineering.

Wei Ding, Xiao-Min Yang, Yu-Tong Yang et al. · 0 citations

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