Author

Wei-Dong He

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Review Open access Sep 2026

Association between HOMA-IR and coexisting MASLD and type 2 diabetes: Insights from NHANES and network pharmacology

Background Insulin resistance is a common metabolic feature of metabolic dysfunction-associated steatotic liver disease (MASLD) and type 2 diabetes (T2D), but its cross-sectional association with the coexistence of these conditions remains incompletely characterized. Objectives To evaluate the associations between the...

Xian-pei Heng, Liu-Qing Yang, Qi-Wei Chen et al. · Therapeutic Advances in Endo... · 0 citations

Open access Aug 2026

Astragalus polysaccharide alleviates neuropathology and cognitive deficits by modulating gut microbiota and neuroinflammation in an Alzheimer’s disease model

Findings demonstrate that APS alleviates cognitive deficits and AD-like pathology, partially through remodeling gut microbiota and modulating the gut-brain axis, and represents a promising natural compound-based therapeutic candidate for managing cognitive decline associated with Alzheimer’s disease.

Xiaolin Cui, Zhen Wei, Qingshui Wang et al. · Frontiers in Pharmacology · 0 citations