Sensorineural hearing loss is driven by disruption of cochlear homeostasis, where dysregulated redox, ionic, and metabolic factors lead to hair cell degeneration and synaptic injury. Current strategies lack the capacity to restore the enzymatic clearance of reactive oxygen species or penetrate the blood-labyrinth barri...
Bao-Ying Xu, Xin-Rui Chen, Kai-Xuan Hu et al.· Nature Communications· 0 citations
Conjugated polymer‐based phototheranostics have attracted considerable attention for cancer treatment owing to their excellent photothermal properties and biocompatibility. However, integrating efficient photodynamic activity into conjugated polymer systems without compromising their intrinsic photothermal performanc...
Xiang-Mei Wen, Meng Chen, Xue-Yan Yao et al.· Advanced Functional Material...· 0 citations
A living bacterial hybrid reactor is developed by integrating Shewanella oneidensis MR-1 with Cu(II)-based zeolitic imidazolate frameworks to enable metabolism-guided and tumor-confined bioorthogonal catalysis, overcoming key limitations of conventional bioorthogonal catalysis and enabling precise, tumor-confined thera...