Open access
Oct 2026
Modulation of Arachidonic Acid Metabolism by Pinoresinol Diglucoside Ameliorates Osteogenic Dysfunction via Coordinated NF-κB Suppression and GSK3β/β-Catenin Activation in Diabetic Osteoporosis.
PDG ameliorates DOP by dual targeting p65 and GSK3β, coordinately inhibiting NF-κB-mediated inflammation and activating the β-catenin osteogenic program, highlighting its therapeutic potential for DOP.
Wen-Qi Jin, Yu-Jing Tan, Lei Zhang et al.
· Phytotherapy Research · 0 citations