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Review Open access Oct 2026

PANoptosis: a novel therapeutic target and mechanistic insight into traditional Chinese medicine intervention in inflammatory bowel disease: a review

The rising incidence of inflammatory bowel disease (IBD) and the limited efficacy of current therapies underscore the need for novel strategies. PANoptosis is an inflammatory programmed cell-death process integrating molecular features of pyroptosis, apoptosis, and necroptosis. Emerging evidence suggests that PANopto...

Xiao-Jiang Li, Wei Guan, Yong-Duo Yu et al. · 0 citations
Open access Sep 2026

Monocyte inflammation and adaptive immune dysfunction in severe Klebsiella pneumoniae pneumonia

Abstract Severe Klebsiella pneumoniae pneumonia is associated with substantial mortality and is characterized by intense systemic inflammation that coexists with a failure to control infection. The cellular changes underlying the transition from effective host defense to immune dysfunction remain incompletely defined....

Hong-Quan Chen, Xiao-Ling Wang, Xiang Liu et al. · 0 citations

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