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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Wei-Hua Fu

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Open access Sep 2026

RIPK3 overcomes 5-fluorouracil resistance in colorectal cancer cells via AKT/mTOR-mediated autophagy

RIPK3 enhances the sensitivity of colorectal cancer cells to 5-FU and increases the efficacy of 5-FU in inhibiting cell proliferation, invasion, and migration by activating cellular autophagy through inhibition of the AKT-mTOR signaling pathway, thereby reversing drug resistance in colorectal cancer cells.

Biao Wang, Xiao-Tong An, Wei-Hua Fu · 0 citations

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