Author

Wei Huang

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Open access Aug 2026

Structural insights into a substrate translocation pathway revealed by the RND efflux pump complex MexJK from Pseudomonas aeruginosa

Resistance–nodulation–cell division (RND) efflux pumps are the major cause of multidrug resistance in Pseudomonas aeruginosa. The inner membrane protein MexK from P. aeruginosa is a narrow-spectrum RND transporter. It assembles with membrane fusion protein MexJ and outer membrane proteins to form a tripartite efflux co...

Zhikun Wu, Ziyue Meng, Wei Huang et al. · Science Advances · 0 citations

Open access Sep 2026

Causal Relationship Between Psoriatic Arthritis and Coronary Heart Disease: A Mendelian Randomization and Bioinformatics Analysis

Objective Psoriatic arthritis (PsA) often coexists with coronary heart disease (CHD). We integrated Mendelian randomization (MR), bioinformatics and reverse network pharmacology to dissect their causality, biomarkers, candidate therapeutics and transcription factors (TFs). Methods With PsA and CHD GWAS statistics, five...

Xie-Tian Yin, Shi-Chao Zhao, Wei Huang et al. · Psoriasis · 0 citations