Macrophage-derived TNF-α promotes vascular inflammation and cell crosstalk in human atherosclerotic plaques via TNFRSF1A.
AIMS Atherosclerosis (AS) is a chronic inflammatory disease driven by complex cellular crosstalk within plaques. How a key inflammatory pathway orchestrates multicellular vascular injury and whether this is conserved across vascular beds remains incompletely understood. METHODS Carotid and coronary plaques were profi...