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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Wei I. Jiang

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Review Open access Oct 2026

Emerging therapeutic strategies to target APOE4 in Alzheimer's disease.

The apolipoprotein E ε4 (APOE4) allele is the strongest common genetic risk factor for late-onset Alzheimer's disease. However, its incomplete penetrance supports the view that it acts as a modifiable systems-level perturbation of brain homeostasis rather than a deterministic driver. Increasing evidence further positio...

Wei I. Jiang, Bing-Ying Wang, Deng-Ke K. Ma · 0 citations

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